Eliminate all of the infected lairs.
Prototype 2 features three different types of hidden collectibles to find; Black Boxes, Infected Lairs and Field Ops Teams. This guide will help you find all 9 Infected Lair locations.
Using the coordinates below on the map, you’ll find the location of each Infected Lair. Just like with the Black Boxes and Field Ops teams, when you get close enough to the location of a Lair, the game will prompt that one is nearby and show the icon on the mini-map. Once found, you must enter the lair and eliminate all of the specified targets inside.
Like the other collectibles, when you find all of the Lairs in each set you will earn a new mutation, and once you have found and destroyed all 9 lairs you will earn the “Spindler’s Search” achievement, worth a cool 40G.